Potent anti‐angiogenesis and anti‐tumour activity of pegaptanib‐loaded tetrahedral DNA nanostructure

OBJECTIVES: Pegaptanib might be a promising anti‐tumour drug targeting VEGF to inhibit tumour vascular endothelial cell proliferation. However, the poor biostability limited its application. In this study, we took tetrahedron DNA nanostructures (TDNs) as drug nanocarrier for pegaptanib to explore th...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Xueping, Zhang, Yuxin, Ma, Wenjuan, Shao, Xiaoru, Zhan, Yuxi, Mao, Chenchen, Zhu, Bofeng, Zhou, Yi, Zhao, Hu, Cai, Xiaoxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797503/
https://www.ncbi.nlm.nih.gov/pubmed/31364793
http://dx.doi.org/10.1111/cpr.12662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797503/
https://www.ncbi.nlm.nih.gov/pubmed/31364793
http://dx.doi.org/10.1111/cpr.12662

Ejemplares similares