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Effects of Bakuchiol on chondrocyte proliferation via the PI3K‐Akt and ERK1/2 pathways mediated by the estrogen receptor for promotion of the regeneration of knee articular cartilage defects

OBJECTIVES: Cartilaginous tissue degradation occurs because of the lack of survival of chondrocytes. Here, we ascertained whether bakuchiol (BAK) has the capability of activating chondrocyte proliferation. MATERIALS AND METHODS: The effect of BAK on the proliferation of rat chondrocytes at a concent...

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Detalles Bibliográficos
Autores principales: Xu, Kang, Sha, Yongqiang, Wang, Sixiang, Chi, Qingjia, Liu, Yanju, Wang, Chunli, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797515/
https://www.ncbi.nlm.nih.gov/pubmed/31407423
http://dx.doi.org/10.1111/cpr.12666