A cis‐eQTL genetic variant in PLK4 confers high risk of hepatocellular carcinoma

PURPOSE: The overexpression and knockdown of PLK4 were both reported to generate aneuploidy. Thus, we aimed to investigate whether genetic variants in PLK4 contribute to the development of hepatocellular carcinoma (HCC). METHODS: We evaluated associations of common variants in PLK4 and its promoter...

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Detalles Bibliográficos
Autores principales: Meng, Lijuan, Zhou, Yan, Ju, Sihan, Han, Jing, Song, Ci, Kong, Jing, Wu, Yifei, Lu, Shuai, Xu, Jiani, Yuan, Wenwen, Zhang, Erbao, Wang, Cheng, Hu, Zhibin, Gu, Yayun, Luo, Rongcheng, Wang, Xuehao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Prevention
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797585/
https://www.ncbi.nlm.nih.gov/pubmed/31489978
http://dx.doi.org/10.1002/cam4.2487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797585/
https://www.ncbi.nlm.nih.gov/pubmed/31489978
http://dx.doi.org/10.1002/cam4.2487

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