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Switch of NAD Salvage to de novo Biosynthesis Sustains SIRT1-RelB-Dependent Inflammatory Tolerance

A typical inflammatory response sequentially progresses from pro-inflammatory, immune suppressive to inflammatory repairing phases. Although the physiological inflammatory response resolves in time, severe acute inflammation usually sustains immune tolerance and leads to high mortality, yet the unde...

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Detalles Bibliográficos
Autores principales: Zhang, Jingpu, Tao, Jie, Ling, Yun, Li, Feng, Zhu, Xuewei, Xu, Li, Wang, Mei, Zhang, Shuye, McCall, Charles E., Liu, Tie Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797595/
https://www.ncbi.nlm.nih.gov/pubmed/31681271
http://dx.doi.org/10.3389/fimmu.2019.02358