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Switch of NAD Salvage to de novo Biosynthesis Sustains SIRT1-RelB-Dependent Inflammatory Tolerance
A typical inflammatory response sequentially progresses from pro-inflammatory, immune suppressive to inflammatory repairing phases. Although the physiological inflammatory response resolves in time, severe acute inflammation usually sustains immune tolerance and leads to high mortality, yet the unde...
Autores principales: | Zhang, Jingpu, Tao, Jie, Ling, Yun, Li, Feng, Zhu, Xuewei, Xu, Li, Wang, Mei, Zhang, Shuye, McCall, Charles E., Liu, Tie Fu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797595/ https://www.ncbi.nlm.nih.gov/pubmed/31681271 http://dx.doi.org/10.3389/fimmu.2019.02358 |
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