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The Orphan Cytokine Receptor CRLF3 Emerged With the Origin of the Nervous System and Is a Neuroprotective Erythropoietin Receptor in Locusts

The orphan cytokine receptor-like factor 3 (CRLF3) was identified as a neuroprotective erythropoietin receptor in locust neurons and emerged with the evolution of the eumetazoan nervous system. Human CRLF3 belongs to class I helical cytokine receptors that mediate pleiotropic cellular reactions to i...

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Detalles Bibliográficos
Autores principales: Hahn, Nina, Büschgens, Luca, Schwedhelm-Domeyer, Nicola, Bank, Sarah, Geurten, Bart R. H., Neugebauer, Pia, Massih, Bita, Göpfert, Martin C., Heinrich, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797617/
https://www.ncbi.nlm.nih.gov/pubmed/31680856
http://dx.doi.org/10.3389/fnmol.2019.00251