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The Orphan Cytokine Receptor CRLF3 Emerged With the Origin of the Nervous System and Is a Neuroprotective Erythropoietin Receptor in Locusts
The orphan cytokine receptor-like factor 3 (CRLF3) was identified as a neuroprotective erythropoietin receptor in locust neurons and emerged with the evolution of the eumetazoan nervous system. Human CRLF3 belongs to class I helical cytokine receptors that mediate pleiotropic cellular reactions to i...
Autores principales: | Hahn, Nina, Büschgens, Luca, Schwedhelm-Domeyer, Nicola, Bank, Sarah, Geurten, Bart R. H., Neugebauer, Pia, Massih, Bita, Göpfert, Martin C., Heinrich, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797617/ https://www.ncbi.nlm.nih.gov/pubmed/31680856 http://dx.doi.org/10.3389/fnmol.2019.00251 |
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