Dynamic Imprinting of the Treg Cell-Specific Epigenetic Signature in Developing Thymic Regulatory T Cells

Regulatory T (Treg) cells mainly develop within the thymus and arise from CD25(+)Foxp3(−) (CD25(+) TregP) or CD25(−)Foxp3(+) (Foxp3(+) TregP) Treg cell precursors resulting in Treg cells harboring distinct transcriptomic profiles and complementary T cell receptor repertoires. The stable and long-ter...

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Detalles Bibliográficos
Autores principales: Herppich, Susanne, Toker, Aras, Pietzsch, Beate, Kitagawa, Yohko, Ohkura, Naganari, Miyao, Takahisa, Floess, Stefan, Hori, Shohei, Sakaguchi, Shimon, Huehn, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797672/
https://www.ncbi.nlm.nih.gov/pubmed/31681278
http://dx.doi.org/10.3389/fimmu.2019.02382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797672/
https://www.ncbi.nlm.nih.gov/pubmed/31681278
http://dx.doi.org/10.3389/fimmu.2019.02382

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