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Dynamic Imprinting of the Treg Cell-Specific Epigenetic Signature in Developing Thymic Regulatory T Cells

Regulatory T (Treg) cells mainly develop within the thymus and arise from CD25(+)Foxp3(−) (CD25(+) TregP) or CD25(−)Foxp3(+) (Foxp3(+) TregP) Treg cell precursors resulting in Treg cells harboring distinct transcriptomic profiles and complementary T cell receptor repertoires. The stable and long-ter...

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Detalles Bibliográficos
Autores principales:	Herppich, Susanne, Toker, Aras, Pietzsch, Beate, Kitagawa, Yohko, Ohkura, Naganari, Miyao, Takahisa, Floess, Stefan, Hori, Shohei, Sakaguchi, Shimon, Huehn, Jochen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797672/ https://www.ncbi.nlm.nih.gov/pubmed/31681278 http://dx.doi.org/10.3389/fimmu.2019.02382

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