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UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells
DNA methylation, repressive histone marks, and PIWI-interacting RNA (piRNA) are essential for the control of retrotransposon silencing in the mammalian germline. However, it remains unknown how these repressive epigenetic pathways crosstalk to ensure retrotransposon silencing in the male germline. H...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797737/ https://www.ncbi.nlm.nih.gov/pubmed/31624244 http://dx.doi.org/10.1038/s41467-019-12455-4 |