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UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells

DNA methylation, repressive histone marks, and PIWI-interacting RNA (piRNA) are essential for the control of retrotransposon silencing in the mammalian germline. However, it remains unknown how these repressive epigenetic pathways crosstalk to ensure retrotransposon silencing in the male germline. H...

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Detalles Bibliográficos
Autores principales: Dong, Juan, Wang, Xiaoli, Cao, Congcong, Wen, Yujiao, Sakashita, Akihiko, Chen, Si, Zhang, Jin, Zhang, Yue, Zhou, Liquan, Luo, Mengcheng, Liu, Mingxi, Liao, Aihua, Namekawa, Satoshi H., Yuan, Shuiqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797737/
https://www.ncbi.nlm.nih.gov/pubmed/31624244
http://dx.doi.org/10.1038/s41467-019-12455-4