Cargando…

Endoplasmic reticulum stress differentially modulates the IL-6 family of cytokines in murine astrocytes and macrophages

In many diseases, misfolded proteins accumulate within the endoplasmic reticulum (ER), leading to ER stress. In response, the cell initiates the unfolded protein response (UPR) to reestablish homeostasis. Additionally, in response to ER stress, various cell types mount an inflammatory response invol...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanchez, Cristina L., Sims, Savannah G., Nowery, John D., Meares, Gordon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797742/
https://www.ncbi.nlm.nih.gov/pubmed/31624329
http://dx.doi.org/10.1038/s41598-019-51481-6