Mice with hyper-long telomeres show less metabolic aging and longer lifespans

Short telomeres trigger age-related pathologies and shorter lifespans in mice and humans. In the past, we generated mouse embryonic (ES) cells with longer telomeres than normal (hyper-long telomeres) in the absence of genetic manipulations, which contributed to all mouse tissues. To address whether...

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Detalles Bibliográficos
Autores principales: Muñoz-Lorente, Miguel A., Cano-Martin, Alba C., Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797762/
https://www.ncbi.nlm.nih.gov/pubmed/31624261
http://dx.doi.org/10.1038/s41467-019-12664-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797762/
https://www.ncbi.nlm.nih.gov/pubmed/31624261
http://dx.doi.org/10.1038/s41467-019-12664-x

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