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Mice with hyper-long telomeres show less metabolic aging and longer lifespans
Short telomeres trigger age-related pathologies and shorter lifespans in mice and humans. In the past, we generated mouse embryonic (ES) cells with longer telomeres than normal (hyper-long telomeres) in the absence of genetic manipulations, which contributed to all mouse tissues. To address whether...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797762/ https://www.ncbi.nlm.nih.gov/pubmed/31624261 http://dx.doi.org/10.1038/s41467-019-12664-x |