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Comparative evaluation of affibody- and antibody fragments-based CAIX imaging probes in mice bearing renal cell carcinoma xenografts

Carbonic anhydrase IX (CAIX) is a cancer-associated molecular target for several classes of therapeutics. CAIX is overexpressed in a large fraction of renal cell carcinomas (RCC). Radionuclide molecular imaging of CAIX-expression might offer a non-invasive methodology for stratification of patients...

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Detalles Bibliográficos
Autores principales: Garousi, Javad, Huizing, Fokko J., Vorobyeva, Anzhelika, Mitran, Bogdan, Andersson, Ken G., Leitao, Charles Dahlsson, Frejd, Fredrik Y., Löfblom, John, Bussink, Johan, Orlova, Anna, Heskamp, Sandra, Tolmachev, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797765/
https://www.ncbi.nlm.nih.gov/pubmed/31624303
http://dx.doi.org/10.1038/s41598-019-51445-w