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Folding Free Energy Landscape of Ordered and Intrinsically Disordered Proteins

Folding funnel is the essential concept of the free energy landscape for ordered proteins. How does this concept apply to intrinsically disordered proteins (IDPs)? Here, we address this fundamental question through the explicit characterization of the free energy landscapes of the representative α-h...

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Detalles Bibliográficos
Autores principales: Chong, Song-Ho, Ham, Sihyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797787/
https://www.ncbi.nlm.nih.gov/pubmed/31624293
http://dx.doi.org/10.1038/s41598-019-50825-6