Simulated microgravity inhibits C2C12 myogenesis via phospholipase D2-induced Akt/FOXO1 regulation

The skeletal muscle system has evolved to maintain body posture against a constant gravitational load. Mammalian target of rapamycin (mTOR) regulates the mechanically induced increase in the skeletal muscle mass. In the present study, we investigated mTOR pathway in C2C12 myoblasts in a model of mec...

Descripción completa

Detalles Bibliográficos
Autores principales: Baek, Mi-Ock, Ahn, Chi Bum, Cho, Hye-Jeong, Choi, Ji-Young, Son, Kuk Hui, Yoon, Mee-Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797799/
https://www.ncbi.nlm.nih.gov/pubmed/31624287
http://dx.doi.org/10.1038/s41598-019-51410-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797799/
https://www.ncbi.nlm.nih.gov/pubmed/31624287
http://dx.doi.org/10.1038/s41598-019-51410-7

Ejemplares similares