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Simulated microgravity inhibits C2C12 myogenesis via phospholipase D2-induced Akt/FOXO1 regulation

The skeletal muscle system has evolved to maintain body posture against a constant gravitational load. Mammalian target of rapamycin (mTOR) regulates the mechanically induced increase in the skeletal muscle mass. In the present study, we investigated mTOR pathway in C2C12 myoblasts in a model of mec...

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Detalles Bibliográficos
Autores principales:	Baek, Mi-Ock, Ahn, Chi Bum, Cho, Hye-Jeong, Choi, Ji-Young, Son, Kuk Hui, Yoon, Mee-Sup
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797799/ https://www.ncbi.nlm.nih.gov/pubmed/31624287 http://dx.doi.org/10.1038/s41598-019-51410-7

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