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Human single-chain antibodies that neutralize Pseudomonas aeruginosa-exotoxin A-mediated cellular apoptosis

Targeting bacterial virulence factors directly provides a new paradigm for the intervention and treatment of bacterial diseases. Pseudomonas aeruginosa produces a myriad of virulence factors to cause fatal diseases in humans. In this study, human single-chain antibodies (HuscFvs) that bound to P. ae...

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Detalles Bibliográficos
Autores principales: Santajit, Sirijan, Seesuay, Watee, Mahasongkram, Kodchakorn, Sookrung, Nitat, Ampawong, Sumate, Reamtong, Onrapak, Diraphat, Pornphan, Chaicumpa, Wanpen, Indrawattana, Nitaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797803/
https://www.ncbi.nlm.nih.gov/pubmed/31624289
http://dx.doi.org/10.1038/s41598-019-51089-w