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Human single-chain antibodies that neutralize Pseudomonas aeruginosa-exotoxin A-mediated cellular apoptosis
Targeting bacterial virulence factors directly provides a new paradigm for the intervention and treatment of bacterial diseases. Pseudomonas aeruginosa produces a myriad of virulence factors to cause fatal diseases in humans. In this study, human single-chain antibodies (HuscFvs) that bound to P. ae...
Autores principales: | Santajit, Sirijan, Seesuay, Watee, Mahasongkram, Kodchakorn, Sookrung, Nitat, Ampawong, Sumate, Reamtong, Onrapak, Diraphat, Pornphan, Chaicumpa, Wanpen, Indrawattana, Nitaya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797803/ https://www.ncbi.nlm.nih.gov/pubmed/31624289 http://dx.doi.org/10.1038/s41598-019-51089-w |
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