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Dendritic Cells Generated From Mops condylurus, a Likely Filovirus Reservoir Host, Are Susceptible to and Activated by Zaire Ebolavirus Infection

Ebola virus infection of human dendritic cells (DCs) induces atypical adaptive immune responses and thereby exacerbates Ebola virus disease (EVD). Human DCs, infected with Ebola virus aberrantly express low levels of the DC activation markers CD80, CD86, and MHC class II. The T cell responses ensuin...

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Detalles Bibliográficos
Autores principales: Edenborough, Kathryn M., Bokelmann, Marcel, Lander, Angelika, Couacy-Hymann, Emmanuel, Lechner, Johanna, Drechsel, Oliver, Renard, Bernhard Y., Radonić, Aleksandar, Feldmann, Heinz, Kurth, Andreas, Prescott, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797855/
https://www.ncbi.nlm.nih.gov/pubmed/31681302
http://dx.doi.org/10.3389/fimmu.2019.02414