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High-fat treatment prevents postoperative cognitive dysfunction in a hyperlipidemia model by protecting the blood-brain barrier via Mfsd2a-related signaling

Damage to the blood-brain barrier (BBB) resulting from systemic inflammation caused by surgical trauma is associated with cognitive dysfunction, and individuals with hyperlipidemia are more sensitive to such impairment. The present study was designed to ascertain whether dexmedetomidine (Dex) treatm...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Ping, Liu, Yu-Ru, Chai, Mei, Yang, Hai-Tao, Wang, Guan, Han, Mei, Li, Dong-Bai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797931/
https://www.ncbi.nlm.nih.gov/pubmed/31545471
http://dx.doi.org/10.3892/mmr.2019.10675