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PTEN modulates neurites outgrowth and neuron apoptosis involving the PI3K/Akt/mTOR signaling pathway

The present study aimed to explore the role of the PTEN/Akt/mTOR signaling pathway in the neurite outgrowth and apoptosis of cortical neurons. Cortical neurons were seeded on or adjacent to chondroitin sulfate proteoglycans. The length, number and crossing behavior of the neurites were calculated. I...

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Detalles Bibliográficos
Autores principales: Liu, Shen, Jia, Jun, Zhou, Hengxing, Zhang, Chi, Liu, Lu, Liu, Jun, Lu, Lu, Li, Xueying, Kang, Yi, Lou, Yongfu, Cai, Zhiwei, Ren, Yiming, Kong, Xiaohong, Feng, Shiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797942/
https://www.ncbi.nlm.nih.gov/pubmed/31702028
http://dx.doi.org/10.3892/mmr.2019.10670