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NF-κB-Dependent IFIT3 Induction by HBx Promotes Hepatitis B Virus Replication

Therapeutic administration of type I IFN (IFN-I) is a common treatment option for individuals suffering from hepatitis B virus (HBV) infection. IFN-I therapy, however, has a relatively low response rate in HBV-infected patients and can induce serious side-effects, limiting its clinical efficacy. The...

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Detalles Bibliográficos
Autores principales: Xu, Fengchao, Song, Hongxiao, An, Beiying, Xiao, Qingfei, Cheng, Genhong, Tan, Guangyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797949/
https://www.ncbi.nlm.nih.gov/pubmed/31681236
http://dx.doi.org/10.3389/fmicb.2019.02382