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House dust mite induces Sonic hedgehog signaling that mediates epithelial-mesenchymal transition in human bronchial epithelial cells

Epithelial-mesenchymal transition (EMT) provides a valuable source of fibroblasts that produce extracellular matrix in airway walls. The Sonic hedgehog (SHH) signaling pathway plays an essential role in regulating tissue turnover and homeostasis. SHH is strikingly upregulated in the bronchial epithe...

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Detalles Bibliográficos
Autores principales: Zou, Yimin, Song, Wenjuan, Zhou, Lingxiao, Mao, Yanxiong, Hong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797970/
https://www.ncbi.nlm.nih.gov/pubmed/31702025
http://dx.doi.org/10.3892/mmr.2019.10707