Deficiency of PTEN leads to aberrant chromosome segregation through downregulation of MAD2

Proper spindle formation and accurate chromosome segregation are essential for ensuring mitotic fidelity. Phosphatase and tensin homolog (PTEN) is a multifunctional protein, which is able to maintain the stability of the genome and chromosomes. The present study described an essential role of PTEN i...

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Detalles Bibliográficos
Autores principales: Sun, Zhuo, Lu, Jinqi, Wu, Muyu, Li, Mingyan, Bai, Lu, Shi, Zhenduo, Hao, Lin, Wu, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797992/
https://www.ncbi.nlm.nih.gov/pubmed/31545428
http://dx.doi.org/10.3892/mmr.2019.10668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797992/
https://www.ncbi.nlm.nih.gov/pubmed/31545428
http://dx.doi.org/10.3892/mmr.2019.10668

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