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Curcumin Blocks Cytotoxicity of Enteroaggregative and Enteropathogenic Escherichia coli by Blocking Pet and EspC Proteolytic Release From Bacterial Outer Membrane

Pet and EspC are toxins secreted by enteroaggregative (EAEC) and enteropathogenic (EPEC) diarrheagenic Escherichia coli pathotypes, respectively. Both toxins are members of the Serine Protease Autotransporters of Enterobacteriaceae (SPATEs) family. Pet and EspC are important virulence factors that p...

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Detalles Bibliográficos
Autores principales: Sanchez-Villamil, Javier I., Navarro-Garcia, Fernando, Castillo-Romero, Araceli, Gutierrez-Gutierrez, Filiberto, Tapia, Daniel, Tapia-Pastrana, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798032/
https://www.ncbi.nlm.nih.gov/pubmed/31681620
http://dx.doi.org/10.3389/fcimb.2019.00334