Cargando…

Global Dynamics of Yeast Hsp90 Middle and C-Terminal Dimer Studied by Advanced Sampling Simulations

The Hsp90 protein complex is one of the most abundant molecular chaperone proteins that assists in folding of a variety of client proteins. During its functional cycle it undergoes large domain rearrangements coupled to the hydrolysis of ATP and association or dissociation of domain interfaces. In o...

Descripción completa

Detalles Bibliográficos
Autores principales: Kandzia, Florian, Ostermeir, Katja, Zacharias, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798034/
https://www.ncbi.nlm.nih.gov/pubmed/31681792
http://dx.doi.org/10.3389/fmolb.2019.00093