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Frontal Contribution to Hippocampal Hyperactivity During Memory Encoding in Aging

Hippocampal hypo- as well as hyper-activation have been reported during memory encoding in older individuals. Prefrontal cortex (PFC) provides top-down state signals to the hippocampus that bias its computation during memory encoding and retrieval, and disturbed top-down signals could contribute to...

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Detalles Bibliográficos
Autores principales: Nyberg, Lars, Andersson, Micael, Lundquist, Anders, Salami, Alireza, Wåhlin, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798051/
https://www.ncbi.nlm.nih.gov/pubmed/31680849
http://dx.doi.org/10.3389/fnmol.2019.00229