CSF Cholinergic Index, a New Biomeasure of Treatment Effect in Patients With Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive disease with early degeneration of the central cholinergic neurons. Currently, three of four AD drugs act by inhibiting the acetylcholine (ACh) degrading enzyme, acetylcholinesterase (AChE). Efficacy of these drugs depends on available amount of ACh, which i...

Descripción completa

Detalles Bibliográficos
Autores principales: Karami, Azadeh, Eriksdotter, Maria, Kadir, Ahmadul, Almkvist, Ove, Nordberg, Agneta, Darreh-Shori, Taher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798072/
https://www.ncbi.nlm.nih.gov/pubmed/31680850
http://dx.doi.org/10.3389/fnmol.2019.00239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798072/
https://www.ncbi.nlm.nih.gov/pubmed/31680850
http://dx.doi.org/10.3389/fnmol.2019.00239

Ejemplares similares