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Engineered T Cell Therapy for Cancer in the Clinic

T cells play a key role in cell-mediated immunity, and strategies to genetically modify T cells, including chimeric antigen receptor (CAR) T cell therapy and T cell receptor (TCR) T cell therapy, have achieved substantial advances in the treatment of malignant tumors. In clinical trials, CAR-T cell...

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Detalles Bibliográficos
Autores principales: Zhao, Lijun, Cao, Yu J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798078/
https://www.ncbi.nlm.nih.gov/pubmed/31681259
http://dx.doi.org/10.3389/fimmu.2019.02250