Glycine 29 Is Critical for Conformational Changes of the Spike Glycoprotein of Mouse Hepatitis Virus A59 Triggered by either Receptor Binding or High pH

Mouse hepatitis virus (MHV) uses its N-terminal domain (NTD) of the viral spike (S) protein to bind the host receptor mouse carcinoembryonic antigen-related cell adhesion molecule 1a (mCEACAM1a) and mediate virus entry. Our previous crystal structure study of the MHV NTD/mCEACAM1a complex (G. Peng,...

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Detalles Bibliográficos
Autores principales: Mi, Dan, Ou, Xiuyuan, Li, Pei, Peng, Guiqing, Liu, Yan, Guo, Ruixuan, Mu, Zhixia, Li, Fang, Holmes, Kathryn, Qian, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798120/
https://www.ncbi.nlm.nih.gov/pubmed/31375571
http://dx.doi.org/10.1128/JVI.01046-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798120/
https://www.ncbi.nlm.nih.gov/pubmed/31375571
http://dx.doi.org/10.1128/JVI.01046-19

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