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Translational Approaches Targeting Ceramide Generation From Sphingomyelin in T Cells to Modulate Immunity in Humans

In T cells, as in all other cells of the body, sphingolipids form important structural components of membranes. Due to metabolic modifications, sphingolipids additionally play an active part in the signaling of cell surface receptors of T cells like the T cell receptor or the co-stimulatory molecule...

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Detalles Bibliográficos
Autores principales: Hollmann, Claudia, Wiese, Teresa, Dennstädt, Fabio, Fink, Julian, Schneider-Schaulies, Jürgen, Beyersdorf, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798155/
https://www.ncbi.nlm.nih.gov/pubmed/31681273
http://dx.doi.org/10.3389/fimmu.2019.02363