Aerobic Exercise Ameliorates Myocardial Inflammation, Fibrosis and Apoptosis in High-Fat-Diet Rats by Inhibiting P2X7 Purinergic Receptors

BACKGROUND: High-fat-diet (HFD) is associated with chronic low-grade inflammation. P2X7 purinergic receptors (P2X7R) are key regulators of inflammasome activation. The benefits of exercise are partly attributed to its anti-inflammatory effect, but whether it regulates P2X7R expression to improve rem...

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Detalles Bibliográficos
Autores principales: Chen, Xudong, Li, Haiyan, Wang, Kangwei, Liang, Xiaohe, Wang, Weiqi, Hu, Xiaokang, Huang, Zhouqing, Wang, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798156/
https://www.ncbi.nlm.nih.gov/pubmed/31681001
http://dx.doi.org/10.3389/fphys.2019.01286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798156/
https://www.ncbi.nlm.nih.gov/pubmed/31681001
http://dx.doi.org/10.3389/fphys.2019.01286

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