Cargando…

Aerobic Exercise Ameliorates Myocardial Inflammation, Fibrosis and Apoptosis in High-Fat-Diet Rats by Inhibiting P2X7 Purinergic Receptors

BACKGROUND: High-fat-diet (HFD) is associated with chronic low-grade inflammation. P2X7 purinergic receptors (P2X7R) are key regulators of inflammasome activation. The benefits of exercise are partly attributed to its anti-inflammatory effect, but whether it regulates P2X7R expression to improve rem...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Xudong, Li, Haiyan, Wang, Kangwei, Liang, Xiaohe, Wang, Weiqi, Hu, Xiaokang, Huang, Zhouqing, Wang, Yonghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798156/ https://www.ncbi.nlm.nih.gov/pubmed/31681001 http://dx.doi.org/10.3389/fphys.2019.01286

Ejemplares similares

Aerobic Exercise Inhibited P2X7 Purinergic Receptors to Improve Cardiac Remodeling in Mice With Type 2 Diabetes
por: Wang, Ting, et al.
Publicado: (2022)

Exercise ameliorates high fat diet induced cardiac dysfunction by increasing interleukin 10
por: Kesherwani, Varun, et al.
Publicado: (2015)

Purinergic signaling in inflammatory renal disease
por: Arulkumaran, Nishkantha, et al.
Publicado: (2013)

Purinergic and Adenosinergic Signaling in Pancreatobiliary Diseases
por: Faraoni, Erika Y., et al.
Publicado: (2022)

Effect of aerobic exercise and low-carbohydrate high-fat diet on glucose tolerance and android/gynoid fat in overweight/obese women: A randomized controlled trial
por: Valsdottir, Thorhildur Ditta, et al.
Publicado: (2023)

Aerobic Exercise Improves Pulmonary Fibrosis by Improving Insulin Resistance and Inflammation in Obese Mice
por: Wang, Xishuai, et al.
Publicado: (2022)

The Effect of Dysglycaemia on Changes in Pulmonary and Aerobic Function in Cystic Fibrosis
por: Tomlinson, Owen W., et al.
Publicado: (2022)

Moderate Physical Training Ameliorates Cardiovascular Dysfunction Induced by High Fat Diet After Cessation of Training in Adult Rats
por: Tófolo, Laize Peron, et al.
Publicado: (2019)

Amelioration of Ambient Particulate Matter (PM(2.5))-Induced Lung Injury in Rats by Aerobic Exercise Training
por: Qin, Fei, et al.
Publicado: (2021)

Colligative Property of ATP: Implications for Enteric Purinergic Neuromuscular Neurotransmission
por: Chaudhury, Arun, et al.
Publicado: (2016)

BYD Ameliorates Oxidative Stress-Induced Myocardial Apoptosis in Heart Failure Post-Acute Myocardial Infarction via the P38 MAPK-CRYAB Signaling Pathway
por: Zhang, Yi, et al.
Publicado: (2018)

Polyene Phosphatidylcholine Ameliorates High Fat Diet-Induced Non-alcoholic Fatty Liver Disease via Remodeling Metabolism and Inflammation
por: Lu, Yang, et al.
Publicado: (2022)

Role of Pannexin-1 hemichannels and purinergic receptors in the pathogenesis of human diseases
por: Velasquez, Stephani, et al.
Publicado: (2014)

Hypoxia induces purinergic receptor signaling to disrupt endothelial barrier function
por: Raghavan, Somasundaram, et al.
Publicado: (2022)

The Influence of Different Fat Sources on Steatohepatitis and Fibrosis Development in the Western Diet Mouse Model of Non-alcoholic Steatohepatitis (NASH)
por: Drescher, Hannah K., et al.
Publicado: (2019)

A High Fat Diet during Adolescence in Male Rats Negatively Programs Reproductive and Metabolic Function Which Is Partially Ameliorated by Exercise
por: Ibáñez, Carlos A., et al.
Publicado: (2017)

Purinergic Signaling in Neuron-Astrocyte Interactions, Circadian Rhythms, and Alcohol Use Disorder
por: Lindberg, Daniel, et al.
Publicado: (2018)

Pathophysiological Role of Purinergic P2X Receptors in Digestive System Diseases
por: An, Qimin, et al.
Publicado: (2021)

P2X7 Receptor Deficiency Ameliorates STZ-induced Cardiac Damage and Remodeling Through PKCβ and ERK
por: Huang, Shanjun, et al.
Publicado: (2021)

Bosutinib Therapy Ameliorates Lung Inflammation and Fibrosis in Experimental Silicosis
por: Carneiro, Priscila J., et al.
Publicado: (2017)

Ceria nanoparticles ameliorate renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis
por: Wang, Mengling, et al.
Publicado: (2022)

Ionotropic P2X ATP Receptor Channels Mediate Purinergic Signaling in Mouse Odontoblasts
por: Shiozaki, Yuta, et al.
Publicado: (2017)

Effects of Hypoxia on Erythrocyte Membrane Properties—Implications for Intravascular Hemolysis and Purinergic Control of Blood Flow
por: Grygorczyk, Ryszard, et al.
Publicado: (2017)

Mechanosensitivity of Murine Lung Slowly Adapting Receptors: Minimal Impact of Chemosensory, Serotonergic, and Purinergic Signaling
por: Domnik, Nicolle J., et al.
Publicado: (2022)

Effects of a 12-Week Very-Low Carbohydrate High-Fat Diet on Maximal Aerobic Capacity, High-Intensity Intermittent Exercise, and Cardiac Autonomic Regulation: Non-randomized Parallel-Group Study
por: Dostal, Tomas, et al.
Publicado: (2019)

Xylooligosaccharide Modulates Gut Microbiota and Alleviates Colonic Inflammation Caused by High Fat Diet Induced Obesity
por: Fei, Yanquan, et al.
Publicado: (2020)

Magnoflorine Ameliorates Inflammation and Fibrosis in Rats With Diabetic Nephropathy by Mediating the Stability of Lysine-Specific Demethylase 3A
por: Chang, Liang, et al.
Publicado: (2020)

Protective Effect of Purinergic P2X7 Receptor Inhibition on Acrolein-Induced Urothelial Cell Damage
por: Taidi, Zhinoos, et al.
Publicado: (2022)

Osthole Ameliorates Renal Fibrosis in Mice by Suppressing Fibroblast Activation and Epithelial-Mesenchymal Transition
por: Zhang, Suping, et al.
Publicado: (2018)

Chlorophyllin Modulates Gut Microbiota and Inhibits Intestinal Inflammation to Ameliorate Hepatic Fibrosis in Mice
por: Zheng, Han, et al.
Publicado: (2018)

High Fat With High Sucrose Diet Leads to Obesity and Induces Myodegeneration
por: Rasool, Suhail, et al.
Publicado: (2018)

High Fat Diet Dysbiotic Mechanism of Decreased Gingival Blood Flow
por: Stanisic, Dragana, et al.
Publicado: (2021)

PTX3 Predicts Myocardial Damage and Fibrosis in Duchenne Muscular Dystrophy
por: Farini, Andrea, et al.
Publicado: (2020)

Insulin Therapy is Associated With Increased Myocardial Interstitial Fibrosis and Cardiomyocyte Apoptosis in a Rodent Model of Experimental Diabetes
por: Adel, Fadi W., et al.
Publicado: (2022)

Echocardiographic myocardial work in pre-adolescent male basketball players: a comparison with cardiopulmonary exercise test-derived aerobic capacity
por: Zhao, Kewei, et al.
Publicado: (2022)

Skeletal Muscle Mitochondrial Bioenergetics and Morphology in High Fat Diet Induced Obesity and Insulin Resistance: Focus on Dietary Fat Source
por: Putti, Rosalba, et al.
Publicado: (2016)

High Fat Diet Decreases Neuronal Activation in the Brain Induced by Resistin and Leptin
por: Alsuhaymi, Naif, et al.
Publicado: (2017)

Lesion Genotype Modifies High-Fat Diet Effects on Endometriosis Development in Mice
por: Heard-Lipsmeyer, Melissa E., et al.
Publicado: (2021)

Fitness-Dependent Effect of Acute Aerobic Exercise on Executive Function
por: Li, Lin, et al.
Publicado: (2019)

The Molecular Mechanism of Aerobic Exercise Improving Vascular Remodeling in Hypertension
por: Song, Yinping, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8np9av2isce0q6sds9ola1p91c