TSHR Signaling Stimulates Proliferation Through PI3K/Akt and Induction of miR-146a and miR-155 in Thyroid Eye Disease Orbital Fibroblasts

PURPOSE: To investigate the molecular pathways that drive thyroid stimulating hormone receptor (TSHR)–induced cellular proliferation in orbital fibroblasts (OFs) from thyroid eye disease (TED) patients. METHODS: Orbital fibroblasts from TED and non-TED patients were treated with TSH and changes in g...

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Detalles Bibliográficos
Autores principales: Woeller, Collynn F., Roztocil, Elisa, Hammond, Christine, Feldon, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798326/
https://www.ncbi.nlm.nih.gov/pubmed/31622470
http://dx.doi.org/10.1167/iovs.19-27865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798326/
https://www.ncbi.nlm.nih.gov/pubmed/31622470
http://dx.doi.org/10.1167/iovs.19-27865

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