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Tumour heterogeneity revealed by unsupervised decomposition of dynamic contrast-enhanced magnetic resonance imaging is associated with underlying gene expression patterns and poor survival in breast cancer patients

BACKGROUND: Heterogeneity is a common finding within tumours. We evaluated the imaging features of tumours based on the decomposition of tumoural dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data to identify their prognostic value for breast cancer survival and to explore their bio...

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Detalles Bibliográficos
Autores principales: Fan, Ming, Xia, Pingping, Liu, Bin, Zhang, Lin, Wang, Yue, Gao, Xin, Li, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798414/
https://www.ncbi.nlm.nih.gov/pubmed/31623683
http://dx.doi.org/10.1186/s13058-019-1199-8