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Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumors

The interplay between the immune system and tumor progression is well recognized. However, current human breast cancer immunophenotyping studies are mostly focused on primary tumors with metastatic breast cancer lesions remaining largely understudied. To address this gap, we examined exome-capture R...

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Detalles Bibliográficos
Autores principales: Zhu, Li, Narloch, Jessica L., Onkar, Sayali, Joy, Marion, Broadwater, Gloria, Luedke, Catherine, Hall, Allison, Kim, Rim, Pogue-Geile, Katherine, Sammons, Sarah, Nayyar, Naema, Chukwueke, Ugonma, Brastianos, Priscilla K., Anders, Carey K., Soloff, Adam C., Vignali, Dario A. A., Tseng, George C., Emens, Leisha A., Lucas, Peter C., Blackwell, Kimberly L., Oesterreich, Steffi, Lee, Adrian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798422/
https://www.ncbi.nlm.nih.gov/pubmed/31627744
http://dx.doi.org/10.1186/s40425-019-0755-1