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pH-triggered endosomal escape of pore-forming Listeriolysin O toxin-coated gold nanoparticles
BACKGROUND: A major bottleneck in drug delivery is the breakdown and degradation of the delivery system through the endosomal/lysosomal network of the host cell, hampering the correct delivery of the drug of interest. In nature, the bacterial pathogen Listeria monocytogenes has developed a strategy...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798460/ https://www.ncbi.nlm.nih.gov/pubmed/31623647 http://dx.doi.org/10.1186/s12951-019-0543-6 |