Cargando…

pH-triggered endosomal escape of pore-forming Listeriolysin O toxin-coated gold nanoparticles

BACKGROUND: A major bottleneck in drug delivery is the breakdown and degradation of the delivery system through the endosomal/lysosomal network of the host cell, hampering the correct delivery of the drug of interest. In nature, the bacterial pathogen Listeria monocytogenes has developed a strategy...

Descripción completa

Detalles Bibliográficos
Autores principales: Plaza-GA, Ismael, Manzaneda-González, Vanesa, Kisovec, Matic, Almendro-Vedia, Víctor, Muñoz-Úbeda, Mónica, Anderluh, Gregor, Guerrero-Martínez, Andrés, Natale, Paolo, López Montero, Iván
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798460/
https://www.ncbi.nlm.nih.gov/pubmed/31623647
http://dx.doi.org/10.1186/s12951-019-0543-6