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3005 Integrin Mac-1 Potentiates Neutrophil Adhesion and NET Release in Antiphospholipid Syndrome

OBJECTIVES/SPECIFIC AIMS: While the role of antiphospholipid antibodies in activating endothelial cells has been extensively studied, the impact of these antibodies on the adhesive potential of leukocytes has received considerably less attention. Mac-1 is a heterodimeric beta-2 integrin primarily ex...

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Detalles Bibliográficos
Autores principales: Sule, Gautam, Kelley, William J., Yalavarthi, Srilakshmi, Eniola-Adefeso, Omolola, Knight, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798700/
http://dx.doi.org/10.1017/cts.2019.36