Thrombin induces Ca(2+)-dependent glutamate release from RPE cells mediated by PLC/PKC and reverse Na(+)/Ca(2+) exchange

PURPOSE: We analyzed the molecular mechanisms leading to glutamate release from rat primary cultures of RPE cells, under isosmotic conditions. Thrombin has been shown to stimulate glutamate release from astrocytes and retinal glia; however, the effect of thrombin on glutamate release from RPE cells...

Descripción completa

Detalles Bibliográficos
Autores principales: López, Edith, Lee-Rivera, Irene, Alvarez-Arce, Alejandro, López-Colomé, Ana María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798708/
https://www.ncbi.nlm.nih.gov/pubmed/31673221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798708/
https://www.ncbi.nlm.nih.gov/pubmed/31673221

Ejemplares similares