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Thrombin induces Ca(2+)-dependent glutamate release from RPE cells mediated by PLC/PKC and reverse Na(+)/Ca(2+) exchange
PURPOSE: We analyzed the molecular mechanisms leading to glutamate release from rat primary cultures of RPE cells, under isosmotic conditions. Thrombin has been shown to stimulate glutamate release from astrocytes and retinal glia; however, the effect of thrombin on glutamate release from RPE cells...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Molecular Vision
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798708/ https://www.ncbi.nlm.nih.gov/pubmed/31673221 |