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To be or not to be pink(1): contradictory findings in an animal model for Parkinson’s disease

The PTEN-induced putative kinase 1 knockout rat (Pink1(−/−)) is marketed as an established model for Parkinson’s disease, characterized by development of motor deficits and progressive degeneration of half the dopaminergic neurons in the substantia nigra pars compacta by 8 months of age. In this stu...

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Detalles Bibliográficos
Autores principales: de Haas, Ria, Heltzel, Lisa C M W, Tax, Denise, van den Broek, Petra, Steenbreker, Hilbert, Verheij, Michel M M, Russel, Frans G M, Orr, Adam L, Nakamura, Ken, Smeitink, Jan A M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798789/
https://www.ncbi.nlm.nih.gov/pubmed/31667474
http://dx.doi.org/10.1093/braincomms/fcz016