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Identification of subsets of IDH-mutant glioblastomas with distinct epigenetic and copy number alterations and stratified clinical risks

BACKGROUND: IDH-mutant glioblastoma is classified by the 2016 CNS WHO as a group with good prognosis. However, the actual number of cases examined in the literature is relatively small. We hypothesize that IDH-mutant glioblastoma is not a uniform group and should be further stratified. METHODS: We c...

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Detalles Bibliográficos
Autores principales: Li, Kay Ka-Wai, Shi, Zhi-Feng, Malta, Tathiane M, Chan, Aden Ka-Yin, Cheng, Shaz, Kwan, Johnny Sheung Him, Yang, Rui Ryan, Poon, Wai Sang, Mao, Ying, Noushmehr, Houtan, Chen, Hong, Ng, Ho-Keung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798792/
https://www.ncbi.nlm.nih.gov/pubmed/31667475
http://dx.doi.org/10.1093/noajnl/vdz015