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A systematic review of the genetic mechanisms of dolutegravir resistance

BACKGROUND: Characterizing the mutations selected by the integrase strand transfer inhibitor (INSTI) dolutegravir and their effects on susceptibility is essential for identifying viruses less likely to respond to dolutegravir therapy and for monitoring persons with virological failure (VF) on dolute...

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Detalles Bibliográficos
Autores principales: Rhee, Soo-Yon, Grant, Philip M, Tzou, Philip L, Barrow, Geoffrey, Harrigan, P Richard, Ioannidis, John P A, Shafer, Robert W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798839/
https://www.ncbi.nlm.nih.gov/pubmed/31280314
http://dx.doi.org/10.1093/jac/dkz256