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QSAR Modelling to Identify LRRK2 Inhibitors for Parkinson’s Disease

Parkinson’s disease is one of the most common neurodegenerative illnesses in older persons and the leucine-rich repeat kinase 2 (LRRK2) is an auspicious target for its pharmacological treatment. In this work, quantitative structure–activity relationship (QSAR) models for identification of putative i...

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Detalles Bibliográficos
Autores principales: Sebastián-Pérez, Víctor, Martínez, María Jimena, Gil, Carmen, Campillo, Nuria Eugenia, Martínez, Ana, Ponzoni, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798859/
https://www.ncbi.nlm.nih.gov/pubmed/30763264
http://dx.doi.org/10.1515/jib-2018-0063