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EMT-Mediated Acquired EGFR-TKI Resistance in NSCLC: Mechanisms and Strategies
Acquired resistance inevitably limits the curative effects of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), which represent the classical paradigm of molecular-targeted therapies in non-small-cell lung cancer (NSCLC). How to break such a bottleneck becomes a pressing probl...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798878/ https://www.ncbi.nlm.nih.gov/pubmed/31681582 http://dx.doi.org/10.3389/fonc.2019.01044 |