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EMT-Mediated Acquired EGFR-TKI Resistance in NSCLC: Mechanisms and Strategies

Acquired resistance inevitably limits the curative effects of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), which represent the classical paradigm of molecular-targeted therapies in non-small-cell lung cancer (NSCLC). How to break such a bottleneck becomes a pressing probl...

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Detalles Bibliográficos
Autores principales:	Zhu, Xuan, Chen, Lijie, Liu, Ling, Niu, Xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798878/ https://www.ncbi.nlm.nih.gov/pubmed/31681582 http://dx.doi.org/10.3389/fonc.2019.01044

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