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Behind the Wheel of Epithelial Plasticity in KRAS-Driven Cancers

Cellular plasticity, a feature associated with epithelial-to-mesenchymal transition (EMT), contributes to tumor cell survival, migration, invasion, and therapy resistance. Phenotypic plasticity of the epithelium is a critical feature in multiple phases of human cancer in an oncogene- and tissue-spec...

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Detalles Bibliográficos
Autores principales: Arner, Emily N., Du, Wenting, Brekken, Rolf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798880/
https://www.ncbi.nlm.nih.gov/pubmed/31681587
http://dx.doi.org/10.3389/fonc.2019.01049