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2219: Amyotrophic lateral sclerosis, stem cells and TALENted technology

OBJECTIVES/SPECIFIC AIMS: The current treatment for amyotrophic lateral sclerosis (ALS) includes systemic delivery of neurotrophic factors (NTFs). Although this approach may seem theoretically sound, NTF efficacy within the central nervous system (CNS) is largely limited by the blood-brain barrier....

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Detalles Bibliográficos
Autores principales: Kurani, Shaheen, Madigan, Nicolas, Clark, Karl, Ekker, Stephen, Staff, Nathan, Windebank, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798916/
http://dx.doi.org/10.1017/cts.2017.212