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3579 The role of CypD/mPTP during osteogenic differentiation - a potential target to prevent bone loss

OBJECTIVES/SPECIFIC AIMS: The study aims to further investigate how cyclophilin D (CypD), the key mPTP opening regulator, affects BMSCs fate and to determine potential regulatory mechanisms involved in CypD regulation during osteogenesis. METHODS/STUDY POPULATION: We evaluated CypD mRNA expression i...

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Detalles Bibliográficos
Autores principales: Sautchuk, Rubens, Shares, Brianna H., Eliseev, Roman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6798964/
http://dx.doi.org/10.1017/cts.2019.58